Insights & Resources
Explore learnings from our research and practical resources to help your team to better understand patient support, assess burden across trials, and build strategies that improve adherence and retention.

White paper
A Theory of Change for clinical trials: A framework for improving patient engagement, adherence, retention, and trial efficiency
This white paper introduces Trial Flow’s Theory of Change framework, showing how protocol-aligned patient support can reduce burden, improve understanding, strengthen motivation and support better trial outcomes. It also explains how Trial Flow maps platform features to impact pathways, helping sponsors and CROs move from patient-centred intent to measurable delivery.
Calculator
Site burden assessment calculator
This calculator helps sponsors and CROs assess how much hidden burden their current patient support model may be placing on research sites. In five minutes, teams can identify where site staff face the most pressure, which activities create repeated manual work, how scalable their current approach is, and where better patient-ready support could reduce friction across trial delivery.


Checklist
Digital patient support scalability checklist
This checklist helps sponsors and CROs assess whether their current digital patient support model is truly scalable across studies, sites and patient populations. It highlights common gaps around value and visibility, study-to-study reuse, structured journey support, operational readiness and governance. Designed to help teams identify where fragmented delivery, hidden manual effort or limited reporting may be holding back efficient trial delivery.

Whitepaper
Voices Unheard: Parents of Autistic Children in Paediatric Care
This white paper explores the often-overlooked experiences of parents navigating healthcare systems with their autistic children. Authored by clinical psychologists Dr. Megan Hofmann and Dr. Vicky Queralt, the paper concludes with actionable recommendations tailored for healthcare settings, staff, and families — all aimed at fostering more compassionate, effective, and inclusive care.
Whitepaper
The Benefits of Play in Healthcare Environments
In this whitepaper, we focus on the long-established benefits of play within healthcare settings, highlighting how providing children with information about their healthcare journey in playful ways, along with them sharing their strengths and needs, that healthcare experiences will be significantly improved for all.

Latest Trial Flow Insights
Explore articles on patient support, trial retention, co-design, behavioural science and scalable delivery across clinical trials.

The ‘last mile’ of recruitment: Supporting patients before they say yes
Explore how better pre-enrolment support improves patient experience, strengthens retention, and shortens trial timelines without increasing site burden.

My Zone and Unwind: Dedicated support for children and teens participating in clinical trials
How a clear place to manage worries, stay calm and feel prepared supports adherence and retention in trials.
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Rethinking retention strategy: The ROI of proactive planning in clinical trials
Proactive retention strategies in clinical trials reduce costs, improve data quality, and protect ROI. Learn why retention must be built into study design from the start.
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