Accelerate your paediatric clinical trials with an integrated participant support system.
The Problem
According to the FDA, 25-40% of paediatric clinical trials fail to establish data to determine the safety and effectiveness of the study intervention. This leads to off-label or unlicensed paediatric prescriptions - reported to be as high as 79% and 35% respectively.
Why do trials fail? Running a paediatric clinical trial is inherently complex - challenges in recruitment, adherence to trial protocol and retention of participants are common.
Paediatric clinical trial challenges
Poor recruitment
$1200 - average cost of a failed recruitment
Early withdrawal
20% of patients withdraw from clinical trials
Low adherence
50% adherence to prescribed medication
Delays
80% of clinical trials are delayed
Lost revenue
$8M lost in revenue each day a trial is delayed
Our Solution
Little Journey is a patient engagement and retention tool designed specifically for paediatric clinical trials.
Co-created with children, parents and clinicians, three components work together to deliver an integrated participant support system:
Digital companion app >
Free mobile app for participants. Age-tailored virtual tours familiarise children with the trial site and procedures. Personalised appointment timelines, preparation checklists, and articles provide caregiver support.
Trial activity packs >
Non-digital support for children. Interactive activities and games help families to prepare for visits, use play for soothing and coping skills, and celebrate their progress.
Research site portal >
For research staff to track participant progress and engagement, enter appointment dates, and share key details like contact information and fasting guidelines.
Why use Little Journey for your clinical trial?
Improved Patient Recruitment
Each research site participating in the trial receive access to the Little Journey platform. This facilitates pre-recruitment engagement and allows for easy information delivery to patients eligible to participate in the trial.
Enhanced Adherence
Gamified progress trackers gently encourage children to engage with and adhere to trial protocols. Interactive activities motivate and celebrate continued progress using stickers and milestone acknowledgements.
Better Patient Experience
Little Journey improves participant engagement and satisfaction through end-to-end family support. The app has delivered a 71% increase in family engagement for our partner hospitals!
Expedited Trial Delivery
Streamlined communications between research staff and trial participants, easy tracking of trial progress, and nudge notifications sent via the app ensure patients and staff are informed and working together to progress through the trial.
Reduced Withdrawal
Positive experiences and trial engagement leads to improved participant retention. Furthermore, through a back-end tracking system, research site staff can identify and help families that are struggling on the trial.
Effective Data Capture
Information on each participant’s site interactions and trial progress, plus overall trial oversight though in-app and behaviour data collection.
Fun & Engaging Trial Activity Packs
Play is the universal language of learning. Our non-digital activity packs give participants the space to be children whilst helping them to learn about self-soothing, coping skills, and what to expect during the trial. This helps to reduce anxiety, create positive experiences, and drives adherence and retention.
Access our library of procedure preparation content for paediatric clinical trials
- Phlebotomy
- Physical Examination & Vital Signs
- Subcutaneous Injection
- MRI
- CT
- Endoscopy
- Spirometry
- Surgery
Coming Soon:
- ECG
- X-Ray
- Sleep Studies
- IV Infusion
To discuss how Little Journey could create a bespoke proposal, fully tailored to your clinical trial protocol and procedures, please contact us at: hello@littlejourney.health
References: 1: Pediatric Clinical Trials Market Analysis – Coherent Market Insights (2020). Online: Pediatric Clinical Trials Market Size, Trends, Shares, Insights, Forecast - Coherent Market Insights 2 - Rajeshwari Gore, Preeta K. Chugh*, Chakra D. Tripathi, Yangshen Lhamo and Sandhya Gautam, “Pediatric Off- Label and Unlicensed Drug Use and Its Implications”, Current Clinical Pharmacology (Discontinued) 2017; 12(1) . https://doi.org/10.2174/1574884712666170317161935